A top-of-the-table clash is set in Sweden with Hammarby taking on BK Häcken, while action continues across England, the USA, France, Sweden and Norway.
Find out how to catch our Matildas Abroad in action in our preview.
England
Kicking off in England, Caitlin Foord and Steph Catley's Arsenal will be back in action for the first time since their narrow defeat in the UWCL semi-final second leg when they host Courtney Nevin and Remy Siemsen's Leicester City.
Both sides sit at either end of the table, with the Gunners looking to claim the title, currently sitting in fourth place just 9 points behind the ladder leaders with two games in hand. While the Foxes are fighting to stay in the top flight, just two points shy of relegation.
This game will kick off on Saturday morning at 4:30 am AEST.
Meanwhile, Kyah Simon's Tottenham Hotspur have the tough task of travelling to Manchester to take on the ladder-leaders Manchester United. This game will kick off on Sunday night at 9:30 pm AEST.
Mackenzie Arnold's West Ham United will be looking to bounce back from their 6-2 defeat last month when they take on Lydia Williams' Brighton & Hove Albion, with both keepers expected to line up for their respective sides.
The last meeting between the two sides in the WSL ended in a 5-4 win for the Seagulls, with fans expected for a fantastic game. This game will kick off on Sunday night at 11:00 pm AEST.
Mary Fowler, Hayley Raso and Alanna Kennedy's Manchester City will be aiming to make it three consecutive wins in the WSL when they take on Liverpool.
City finds itself in second place, just three points shy of first place. This game will kick off on Sunday night at 11:00 pm AEST.
Emily Gielnik's Aston Villa looks to squash their three-game unbeaten streak when they take on last-place Reading FC.
Villa suffered a late 3-2 defeat in their last WSL outing, despite opening the scoring early a 93rd-minute matchwinner from Millie Turner handed Manchester United all three points.
This game will kick off on Sunday night at 11:00 pm AEST.
Lastly, Sam Kerr's Chelsea will host Clare Wheeler's Everton, with Emma Hayes' side recording a late 2-1 draw over Liverpool in midweek action, thanks to a winner from Kerr.
The Blues still have a fourth consecutive league title in their sights, sitting four points outside of the top of the table with two games still in hand. Meanwhile, the Toffees come into the game off the back of a 3-2 win over Reading FC.
This game will kick off on Monday morning at 3:45 am AEST.
France
Over in France, Ellie Carpenter's Lyon play their first competitive game since mid-April when they face Dijon. Lyon currently sits at the top of the table, with just one point dividing them and PSG.
Carpenter's side has just three more games in the D1 to hold on to first place, with their task against 10th-placed Dijon set. The last meeting between the two sides ended in an 8-0 win to Lyon. This game will kick off on Saturday night at 9:30 pm AEST.
USA
Moving over to the USA, Emily Van Egmond's San Diego Wave FC will be aiming to bounce back from their second defeat of the season when they travel to Washington to take on the Spirit.
Van Egmond did not feature in Wave's 3-1 defeat to the Orlando Pride, missing the game due to a back injury. This game will kick off on Sunday morning at 3:00 am AEST.
Meanwhile, Alex Chidiac's Racing Louisville is still in search of their first win of the season after four consecutive draws. Racing takes on last place Orlando Pride, whose only points of the season came last weekend in their win over Wave.
Chidiac did not feature in Racing's late 2-2 draw to OL Reign, with her side unable to hold on to a 2-0 lead at the break. This game will kick off on Sunday morning at 9:00 am AEST.
Sweden
In Sweden, Teagan Micah's FC Rosengård will be looking to make it consecutive wins after a slow start to the season when they host Kristianstads DFF.
After lifting the title for the last two seasons, Rosengård sees themselves sitting outside of the top four with only two wins so far. They take on fourth place Kristianstads, with a win for Micah's side seeing them move up to at least fifth on the ladder.
This game will kick off on Saturday morning at 2:00 am AEST.
Meanwhile, Clare Polkinghorne, Katrina Gorry and Charli Grant's Vittsjö GIK will be aiming to build on their 1-0 win in midweek action when they take on IK Uppsala.
Vittsjö GIK's trio of Aussies did not feature in their victory over Växjö DFF on Thursday morning, with their side making it back-to-back wins in their absence. This game will kick off on Sunday night at 11:00 pm AEST.
Lastly, it's a top-of-the-table clash when Kyra Cooney-Cross' undefeated Hammarby take on Aivi Luik's BK Häcken. Hammarby is yet to taste defeat in the season, recording six wins from six to see them occupy first place.
Häcken has recorded five wins and just one draw, with this fixture a taster of what's to come in June's Swedish Women's Cup Final. This game will kick off on Tuesday morning at 3:00 am AEST.
Norway
Our last stop takes us to Norway, where Tameka Yallop and Larissa Crummer's SK Brann will be trying to bounce back from midweek defeat when they take on Røa IL.
The task is all the harder for Brann, with the club announcing throughout the week that Olli Harder would be relieved of his duties as coach after the reigning champions sit in fourth on the table. This game will kick off on Sunday morning at 12:45 am AEST.