Aussies will face off in Sweden as FC Rosengård hosts new CommBank Matildas goalscorer Daniela Galic and Vittsjö GIK.
In the NWSL, Sam Kerr's Gotham FC are five points clear on top of the table with three games remaining, and could take massive strides towards the regular season plate this weekend.
Read our preview of the action below.
England
WSL
Arsenal host Birmingham City on Saturday, 10.45pm AEDT. The Gunners had a rocky start to the season but will be hoping to rejuvenate after the international break and come back stronger. Caitlin Foord, Kyra Cooney-Cross and Steph Catley will be available for Arsenal.
It’s a London derby on Sunday as Chelsea host Tottenham at 10.00pm AEDT. The Blues are at the top of the chasing pack in the early stages of the season and will hope to continue to keep the momentum going against Spurs. Ellie Carpenter will be available for Chelsea, while Clare Hunt remains injured for Tottenham.
London City Lionesses and Everton face off on Monday, 12.00am AEDT. The Lionesses are third on the table and will hope to overcome an Everton side who have shown glimpses of quality throughout the campaign. Alanna Kennedy will hope to make her return from injury for London City while Clare Wheeler and Holly McNamara will be available for Everton.
Charlton Athletic are still looking for their first points as they host Manchester United on Monday, 12.00am AEDT. It’s been a rocky start to the season for Charlton, and the break presents an opportunity for them to turn things around. Emily van Egmond and Leah Davidson will be available for Charlton.
Finally, Manchester City host Brighton & Hove Albion on Monday, 12.30am AEDT. The defending champions have a perfect record to start the season and will hope to continue that against the Seagulls. Mary Fowler will be available for Brighton, while Charlie Rule will hope to make her return from injury for Brighton.
You can watch the WSL on Stan Sport.
League Cup
Nottingham Forest travel to take on Sheffield United on Sunday, 11.00pm AEDT. Alana Murphy and Leticia McKenna will hope to take their form from the international window back to their club as they battle it out against fellow WSL2 opposition.
Newcastle United take on Sunderland on Monday, 12.00am AEDT. The Magpies go into the match as favourites after a fantastic start to the WSL2 season and will hope to continue that form into the cup. Kaitlyn Torpey will be available for Newcastle.
Alexia Apostolakis and Bristol City take on Southampton on Sunday, 1.00am AEDT. Apostolakis made her second appearance for the CommBank Matildas against Haiti and will hope to take what she has learned into this fixture.
Sweden
Malmö FF take on AIK on Saturday, 11.00pm AEDT. A win for Malmö over fourth-place AIK will be huge in ensuring that they finish in the top three and qualify for Europe next season. Amy Sayer, Charli Grant and Courtney Nevin will be available for Malmö.
FC Rosengård host Daniela Galic and Vittsjö GIK on Sunday, 12.00am AEDT. Rosengård are currently two points clear of the relegation playoff, and every point at this stage of the season counts. Remy Siemsen, Bryleeh Henry and Isabel Gomez will be available to face off against Galic on the weekend.
United States
Gotham FC take on Washington Spirit on Sunday, 3.30am AEDT. Gotham are five points clear on top of the table with three games remaining, meaning that a win on the weekend will make it very difficult for any team to chase them down. Sam Kerr will be available for Gotham.
The Portland Thorns take on Bay FC on Monday, 8.00am AEDT. The Thorns need a win to guarantee that they remain in the playoff places – and, so close to the end of the season, every match is vital. Mackenzie Arnold is expected to start in goal for Portland.
You can watch the NWSL on Stan Sport.
Germany
Eintracht Frankfurt take on Leverkusen on Saturday, 11.00pm AEDT. It will be a tight fixture against one of the teams touted to challenge for a European place this season, and could be a six-pointer for the top three. Hayley Raso and Jamilla Rankin will be available for Frankfurt.
Italy
Como clash with Fiorentina on Sunday, 12.00am AEDT. Como are one win and one loss from their two games this season and have designs on finishing in the top half of the table. Alex Chidiac will be available for Como.
AS Roma host AC Milan on Monday, 12.00am AEDT. Winonah Heatley will be available for Roma as they continue to build into their title defence.
Canada
The Calgary Wild take on AFC Toronto on Monday, 4.00am AEDT. Kahli Johnson will be available as the Wild hope to finish their season on a high.
Every points counts for the Vancouver Rise, meanwhile, as they take on the Ottawa Rapid on Monday, 7.00am AEDT. Newly minted CommBank Matilda Tori Tumeth will be a key part of the defence as they look to cling onto a finals spot.
Norway
Vålerenga travel to take on LSK Kvinner on Saturday, 10.00pm AEDT. Hana Lowry will hope to take everything she learned from her first CommBank Matildas call-up as her side looks to finish in European qualification places.